Detalhe da pesquisa
1.
A decision process for drug discovery in retinoblastoma.
Invest New Drugs
; 39(2): 426-441, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33200242
2.
Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation.
Invest New Drugs
; 36(4): 590-600, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29297149
3.
RABiT-III: an Automated Micronucleus Assay at a Non-Specialized Biodosimetry Facility.
Radiat Res
; 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514936
4.
Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons.
Nat Biotechnol
; 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168993
5.
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127.
Science
; 383(6682): eadi5798, 2024 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38301010
6.
TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron.
bioRxiv
; 2023 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37034664
7.
Cavß1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function.
Nat Commun
; 13(1): 2033, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440113
8.
TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma.
Nat Commun
; 13(1): 5676, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167829
9.
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.
Nat Genet
; 53(5): 707-718, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33846634
10.
Clinical, Genomic, and Pharmacological Study of MYCN-Amplified RB1 Wild-Type Metastatic Retinoblastoma.
Cancers (Basel)
; 12(9)2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32971811
11.
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.
Nat Genet
; 51(6): 999-1010, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31110351
12.
Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2.
Dev Cell
; 45(5): 580-594.e7, 2018 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29804876
13.
A pharmaceutical company user's perspective on the potential of high content screening in drug discovery.
Methods Mol Biol
; 356: 19-31, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-16988392
14.
Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations.
JCI Insight
; 2(6): e90196, 2017 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28352655
15.
Microenvironment-derived factors driving metastatic plasticity in melanoma.
Nat Commun
; 8: 14343, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28181494
16.
Prediction of potent shRNAs with a sequential classification algorithm.
Nat Biotechnol
; 35(4): 350-353, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28263295
17.
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.
Nat Genet
; 49(6): 866-875, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28436985
18.
High-throughput confocal microscopy for beta-arrestin-green fluorescent protein translocation G protein-coupled receptor assays using the Evotec Opera.
Methods Enzymol
; 414: 99-120, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17110189
19.
Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens.
FEBS J
; 283(17): 3170-80, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27250066
20.
Using CRISPR/Cas to study gene function and model disease in vivo.
FEBS J
; 283(17): 3194-203, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27149548